Publications
Peer-reviewed
Bracha S, Johnson HJ, Pranckevicius NA, Catto F, Economides AE, Litvinov S, Hassi K, Rigoli MT, Cheroni C, Bonfanti M, Valenti A, Stucchi S, Atrreya S, Ross PD, Walsh D, Malachi N, Livne H, Eshel R, Krupalnik V, Levin D, Cobb, S, Koumoutsakos P, Caporale N, Test G, Aguzzi A, Koshy AA, Sheiner L, Rechavi O. (2024). Nature Microbiology
Toxoplasma type II effector GRA15 has limited influence in vivo.
Merritt EF, Kochanowsky JA, Herve P, Watson AA, Koshy AA, Treeck M. (2024). PLoS One
Butterworth S, Kordova K, Sambamurthy C, Thomas KK, Torelli F, Lockyer EJ, Edwards A, Goldstone R, Koshy AA, Treeck M. (2023). Cell Host & Microbe
A positive feedback loop controls Toxoplasma chronic differentiation.
Licon MH, Giuliano CJ, Chan AW, Chakladar S, Eberhard JN, Shallberg LA, Sambamurthy C, Waldman BS, Koshy AA, Hunter CA, Lourido S. (2023). Nature Microbiology
Understanding neuroinflammation through central nervous system infections.
Johnson HJ, Koshy AA. (2022). Current Opinion in Neurobiology
Sambamurthy C, Kochanowsky JA, Merritt EF, Lagas JS, Swannigan A, Koshy AA. (2022). Nature Communications
Shallberg LA, Phan AT, Christian DA, Perry JA, Haskins BE, Beiting DP, Harris TH, Koshy AA, Hunter CA. (2022). PLoS Pathogens
Injection with Toxoplasma gondii protein affects neuron health and survival.
Mendez OA, Machado EF, Lu J, Koshy AA. (2021). eLife
Kochanowsky JA, Thomas KK, Koshy AA. (2021). mBio
Merritt EF*, Johnson HJ*, Wong ZS, Buntzman AS, Conklin AC, Cabral CM, Romanoski CE, Boyle JP, Koshy AA. (*equal contributors) (2020). mSphere
McGovern KE, Cabral CM, Morrison HW, Koshy AA. (2020). Scientific Reports
Latent Toxoplasmosis Effects on Rodents and Humans: How Much is Real and How Much is Media Hype?
Johnson HJ, Koshy AA. (2020). mBio
The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell Responses.
Chen L, Christian DA, Kochanowsky JA, Phan AT, Clark JT, Wang S, Berry C, Oh J, Chen X, Roos DS, Beiting DP, Koshy AA, Hunter CA. (2020). Journal of Experimental Medicine
Three-Dimensional Reconstruction of Toxoplasma-Neuron Interactions In Situ.
Cabral CM, Merritt EF, Koshy AA. (2020). Methods in Molecular Biology
Tuladhar S, Kochanowsky JA, Bhaskara A, Ghotmi Y, Sambamurthy C, Koshy AA. (2019). PLoS Pathogens
Semi-automated quantification and neuroanatomical mapping of heterogeneous cell populations.
Mendez OA*, Potter CP*, Valdez M, Bello T, Trouard TP, Koshy AA. (*equal contributors) (2018). Journal of Neuroscience Methods
Cabral CM, McGovern KE, McDonald WR, Franco J, Koshy AA. (2017). ASN Neuro
Toxoplasma gondii: Entry, association, and physiological influence on the central nervous system.
Mendez OA, Koshy AA. (2017). PLoS Pathogens
STAT1 signaling in astrocytes is essential for control of infection in the central nervous system.
Hidano S, Randall L, Dawson L, Dietrich HK, Konradt C, Klover PJ, John B, Harris TH, Fang Q, Turek B, Kobayashi T, Hennighausen L, Beiting DP, Koshy AA, Hunter CA. (2016). mBio
Endothelial cells as a replicative niche for pathway entry to the CNS.
Konradt C, Ueno N, Christian DA, Delong J, Harms-Pritchard G, Herz J, Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA. (2016). Nature Microbiology
Neurons are the primary target cell for the brain-tropic intracellular parasite Toxoplasma gondii.
Cabral CM*, Tuladhar S*, Dietrich HK, Nguyen E, MacDonald WR, Trivedi T, Devineni A, Koshy AA. (*equal contributors and listed alphabetically) (2016). PLoS Pathogens
Han SJ, Melichar HJ, Coombes JL, Chan SW, Koshy AA, Boothroyd JC, Barton GM, Robey EA. (2014). Immunol Cell Biol
3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii.
Koshy AA, Cabral CM. (2014).J. Vis. Exp.
Toxoplasma gondii development of its replicative niche: in its host cell and beyond.
Blader IJ, Koshy AA. (2014). Eukaryot Cell.
Christian DA, Koshy AA, Reuter MA, Betts MR, Boothroyd JC, Hunter CA. (2014). Infect Immun.
Astrocytic TGF-β signaling fine-tunes the brain’s immune response to Toxoplasma gondii infection.
Cekanaviciute E, Dietrich HK, Axtell RC, Williams AM, Egusquiza R, Wai KM, Koshy AA*, Buckwalter MS*. (*equal contributors) (2014). J. Immunol.
Dupont CD, Christian DA, Selleck EM, Pepper M, Leney-Greene M, Harms-Pritchard G, Koshy AA, Wagage S, Reuter MA, Sibley LD, Betts MR, Hunter CA. (2014). Plos Pathog.
Coombs JL, Charsar BA, Han SJ, Halkias J, Chan SW, Koshy AA, Striepen B, Robey EA. (2013). PNAS.
Caffaro CE, Koshy AA, Liu L, Zeiner GM, Hirschberg CB, Boothroyd JC. (2013). PLoS Pathogens.
Toxoplasma co-opts host cells it does not invade.
Koshy AA, Dietrich, HK, Christian, DA, Melehani, JH, Shastri, AJ, Hunter, CA, Boothroyd, JC. (2012). PLoS Pathogens.
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.
Koshy AA, Fouts, AE, Lodoen, MB, Alkan, O, Blau, HM, Boothroyd, JC. (2010). Nature Methods.